Cycleon's Ketofin Profile

9MM

I have seen it on other forum's why isn't it here.

9MM

This is the one I'm talking about.

Ketotifen - what you need to know by CYCLEON

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I see a lot of newbie people trying to find good info on this so I thought it would be best to put it all in one place. I patched this from a wide range of sources as well as my own experience (also thanks to FONZ). This truly is a wonderdrug for BB.

What Is It?
Ketotifen is very safe antihistamine used extensively in Europe to treat bronchial asthma and allergies. It is also being studied as a treatment for colitis. When used for asthma, weight gain and an increase in appetite are among the most frequent side effects. Ketotifen also protects the cells in the stomach, small intestine and perhaps the rest of the gut from a number of toxins. A number of case studies suggest that it may be helpful treating skin problems such as acne. Ketotifen also reduces edema (swelling and puffiness caused by water retention) around sores.

Ketotifen Studies
German researchers have published data showing that ketotifen lowers tnf-alpha in the test tube. One study used ketotifen in combination with oxymethadone, a steroid like Megace that helps people gain weight, so it is hard to gauge what effect ketotifen had (the study notes a 14% reduction in TNF-alpha levels and weight gains of 11-12 pounds in less than four weeks). A larger placebo controlled study of this combination is underway. The other study used ketotifen by itself in eight patients with elevated TNF-alpha, (but no wasting). Taking ketotifen for 12 weeks, these patients gained an average of six pounds, had increases in their body cell mass and reductions in their TNF-alpha levels.

Side Effects and Toxicity
Ketotifen is virtually non-toxic (although it is not advised for patients with epilepsy). People who took twenty times the recommended dose (in suicide attempts) suffered no serious consequences (other than embarrassment). Its primary side effects seem to be temporary drowsiness, dry mouth,(and other mucuos membranes) appetite stimulation and weight gain.

Dosing and side effects
No studies have been done to find the most effective dose but the German researchers used 4 mg ED. Dan Duchaine (who discovered ketos use for BB) suggested 10mg ED but in my experience this much is not needed and makes u far too sleepy. I find that 3-4mg ED seems ideal. However, much higher doses have been shown to be quite safe with no adverse affects other than increased drowsiness and appetite – it will make u hungry for solid foods. You can take it divided in the day or all at once but I find I get waay too sleepy if its all at once - not to mention my clen feels like its going to make my heart jump out of my chest, so divided doses is the best IMO.

Ketotifen and Clen Clenbuterol is a beta 2 agonist which has a limited anabolic effect during its first few days of use and afterward is normally used to fight fat. At higher doses, however, it can be catabolic to muscle and it must be cycled on a 2 week on, 2 week of basis or the beta 2 receptors that Clen binds to become saturated and down regulate.

Ketotifen’s magic is that it upregulates the beta-receptors including the beta 2s that Clen uses. As long as you are taking ketotifen, it will continue to clean these receptors, never allowing them to downregulate – even while on a heavy Clen cycle. That means you can continue to take Clen indefinitely without having to cycle off to regenerate the receptors. 2-3mg ED can upregulate even severely shut down receptors within a week.

It also means that you don’t need as much Clen to get the same benefits. It seems u can take about 30-40% less Clen and it be equally effective. FONZ posted that it also increases the number of receptor sites on the surface of the cell, allowing more Clen to attach and perhaps this is the reason for the increased efficacy. Ketotifen also seems to lessen the sides of Clen including the jitters but it can make you drowsy as hell if you take too much at one time. A second benefit is you can use it to knock you out if you cant sleep.

Ketotifen and ECA
Perhaps an even better use for ketotifen is taking it with the ECA stack. While the thermogenic effect of ephedrine is not as potent as Clen because it doesn't have a high receptor affinity, and it is not limited to beta-2 receptors. In fact it seems to have a good effect on beta 3 receptors as well, which act as a type of thermogenic messenger and over half of ephedrine effect is from beta-3 stimulation. Clen has almost no effect on beta 3 however. So by keeping the beta 2 receptors up, ketotifen can allow the benefits of continuous beta 2 and beta 3 stimulation from ephedrine.

Enjoy

TEXAS STRONG

Great post!

LACBodybuilder

It's here now.

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clhp20

LOL, i'm assuming that it wasn't here because hooker thinks it's far from complete. LOL...

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"I don't give a fuck if they see me staring at their tits or cunts either. So if they see me looking and are interested...that turns into more pussy.

JC

CYCLEON

LOL - that was back in the day when I actually got to write such things instead of admin a board and take care of problems behind the scenes like everyone wanting me to fire hooker - hahahhahahah - I used to write stuff on t3, clen/keto, crap...a lot of things that were kinda unusual at the time but making the final decisions at a board takes all the time I have to give.

funny thing is I kept hooker on for awhile just because I think everyone should have a chance - but after awhile it was just tearing AR apart and I told brian that he HAD to go - but even then I gave him a soft out and offered him the opportunity to "resign" so it didnt seem to be an insult - hope he would remember such things but I guess not

I really should update that a bit and put it in our ed files

9MM

I think I missed something.

9MM

Cycleon never made is profile a sticky so I have done it for him

Mallet

I still remember you being the first guy to post up the newest breaking info on almost anything related to performance enhancements, fatloss, etc...even while admin the AR board. You have always gained my respect for your patience with irate members as well. But i guess that's why i'm over here and not over at AR anymore

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There is only one disease known to mankind, though it has a thousand names. It's the disease of too many toxins in the body and too few nutrients reaching the cells.

9MM

Manic was scratching his wee head there thinking when did I do any of that. Then the lightbulb came on. Yeah Cyclone sure knows his stuff.

CYCLEON

whats funny too is that I always gave attribution to others whose work I had read or thought interesting - rather unlike someone else who now has a book out

Mallet

LMAO...that is so true, credit is due where credit is due...i guess some people just lack self confidence and need approval from others to feel important.

Boy if we could all just know everything...what a gift that must be.

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There is only one disease known to mankind, though it has a thousand names. It's the disease of too many toxins in the body and too few nutrients reaching the cells.

TheBrent

good read... I'm takin me and my asthma to Europe for awhile

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Surf's Up

rake922

Coool.

glmys

Great post, but ketofin made me so tired. Even the next day, it just seemed to hang around. The sleep was great on it, but I would watch how much you take of it.

PurePower

Yea Cyc definatly knows his shit